Interleukin-11 alters placentation and causes preeclampsia features in mice

Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and proteinuria after 20 wk gestation. Abnormal extravillous trophoblast (EVT) invasion and remodeling of uterine spiral arterioles is thought to contribute to PE development. Interleukin-11 (IL11) impedes human EVT inv...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Winship, Amy L., Koga, Kaori, Menkhorst, Ellen, Van Sinderen, Michelle, Rainczuk, Katarzyna, Nagai, Miwako, Cuman, Carly, Yap, Joanne, Zhang, Jian-Guo, Simmons, David, Young, Morag J., Dimitriadis, Evdokia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702983/
https://ncbi.nlm.nih.gov/pubmed/26655736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515076112
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