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Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss

The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Specialized trophoblast cells derived from the embryonic trophectoderm play a pivotal role in the establishment of the placenta. Leukemia inhibitory factor (LIF)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Winship, Amy, Correia, Jeanne, Krishnan, Tara, Menkhorst, Ellen, Cuman, Carly, Zhang, Jian-Guo, Nicola, Nicos A., Dimitriadis, Evdokia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536525/
https://ncbi.nlm.nih.gov/pubmed/26272398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13237
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