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HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urgency of understanding the regulatory genome as a key component for translating genetic results into mechanistic insights a...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Ward, Lucas D., Kellis, Manolis
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702929/
https://ncbi.nlm.nih.gov/pubmed/26657631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1340
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