Minor Contribution of Chimeric Host-HIV Readthrough Transcripts to the Level of HIV Cell-Associated gag RNA

Cell-associated HIV unspliced RNA is an important marker of the viral reservoir. HIV gag RNA-specific assays are frequently used to monitor reservoir activation. Because HIV preferentially integrates into actively transcribed genes, some of the transcripts detected by these assays may not represent...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pasternak, Alexander O., DeMaster, Laura K., Kootstra, Neeltje A., Reiss, Peter, O'Doherty, Una, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702708/
https://ncbi.nlm.nih.gov/pubmed/26559833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02597-15
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