Differential Recognition of Influenza A Viruses by M1(58–66) Epitope-Specific CD8(+) T Cells Is Determined by Extraepitopic Amino Acid Residues

Natural influenza A virus infections elicit both virus-specific antibody and CD4(+) and CD8(+) T cell responses. Influenza A virus-specific CD8(+) cytotoxic T lymphocytes (CTLs) contribute to clearance of influenza virus infections. Viral CTL epitopes can display variation, allowing influenza A viru...

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Vydáno v:J Virol
Hlavní autoři: van de Sandt, Carolien E., Kreijtz, Joost H. C. M., Geelhoed-Mieras, Martina M., Nieuwkoop, Nella J., Spronken, Monique I., van de Vijver, David A. M. C., Fouchier, Ron A. M., Osterhaus, Albert D. M. E., Rimmelzwaan, Guus F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702701/
https://ncbi.nlm.nih.gov/pubmed/26537686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02439-15
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