Single Mutations in the VP2 300 Loop Region of the Three-Fold Spike of the Carnivore Parvovirus Capsid Can Determine Host Range

Sylvatic carnivores, such as raccoons, have recently been recognized as important hosts in the evolution of canine parvovirus (CPV), a pandemic pathogen of domestic dogs. Although viruses from raccoons do not efficiently bind the dog transferrin receptor (TfR) or infect dog cells, a single mutation...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Allison, Andrew B., Organtini, Lindsey J., Zhang, Sheng, Hafenstein, Susan L., Holmes, Edward C., Parrish, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Genetic Diversity and Evolution
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702700/
https://ncbi.nlm.nih.gov/pubmed/26512077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02636-15
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares