Global Displacement of Canine Parvovirus by a Host-Adapted Variant: Structural Comparison between Pandemic Viruses with Distinct Host Ranges

Canine parvovirus type 2 (CPV-2) emerged in 1978 and spread worldwide within 2 years. Subsequently, CPV-2 was completely replaced by the variant CPV-2a, which is characterized by four specific capsid (VP2) mutations. The X-ray crystal structure of the CPV-2a capsid shows that each mutation confers s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Organtini, Lindsey J., Allison, Andrew B., Lukk, Tiit, Parrish, Colin R., Hafenstein, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300749/
https://ncbi.nlm.nih.gov/pubmed/25410876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02611-14
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