Structural Insights into HIV-1 Vif-APOBEC3F Interaction

The HIV-1 Vif protein inactivates the cellular antiviral cytidine deaminase APOBEC3F (A3F) in virus-infected cells by specifically targeting it for proteasomal degradation. Several studies identified Vif sequence motifs involved in A3F interaction, whereas a Vif-binding A3F interface was proposed ba...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Nakashima, Masaaki, Ode, Hirotaka, Kawamura, Takashi, Kitamura, Shingo, Naganawa, Yuriko, Awazu, Hiroaki, Tsuzuki, Shinya, Matsuoka, Kazuhiro, Nemoto, Michiko, Hachiya, Atsuko, Sugiura, Wataru, Yokomaku, Yoshiyuki, Watanabe, Nobuhisa, Iwatani, Yasumasa
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Structure and Assembly
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702671/
https://ncbi.nlm.nih.gov/pubmed/26537685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02369-15
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