Sabin Vaccine Reversion in the Field: a Comprehensive Analysis of Sabin-Like Poliovirus Isolates in Nigeria

To assess the dynamics of genetic reversion of live poliovirus vaccine in humans, we studied molecular evolution in Sabin-like poliovirus isolates from Nigerian acute flaccid paralysis cases obtained from routine surveillance. We employed a novel modeling approach to infer substitution and recombina...

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Pubblicato in:J Virol
Autori principali: Famulare, Michael, Chang, Stewart, Iber, Jane, Zhao, Kun, Adeniji, Johnson A., Bukbuk, David, Baba, Marycelin, Behrend, Matthew, Burns, Cara C., Oberste, M. Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Genetic Diversity and Evolution
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702576/
https://ncbi.nlm.nih.gov/pubmed/26468545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01532-15
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