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Viral DNA-Dependent Induction of Innate Immune Response to Hepatitis B Virus in Immortalized Mouse Hepatocytes

Hepatitis B virus (HBV) infects hundreds of millions of people worldwide and causes acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. HBV is an enveloped virus with a relaxed circular (RC) DNA genome. In the nuclei of infected human hepatocytes, conversion of RC DNA from the inco...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cui, Xiuji, Clark, Daniel N., Liu, Kuancheng, Xu, Xiao-Dong, Guo, Ju-Tao, Hu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702573/
https://ncbi.nlm.nih.gov/pubmed/26491170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01263-15
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