Hepatitis C Virus Infection Impairs IRF-7 Translocation and Alpha Interferon Synthesis in Immortalized Human Hepatocytes

Hepatitis C virus (HCV) establishes chronic infection in a significant number of infected humans, although the mechanisms for chronicity remain largely unknown. We have previously shown that HCV infection in immortalized human hepatocytes (IHH) induces beta interferon (IFN-β) expression (T. Kanda, R...

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Main Authors: Raychoudhuri, Amit, Shrivastava, Shubham, Steele, Robert, Dash, Srikanta, Kanda, Tatsuo, Ray, Ranjit, Ray, Ratna B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Cellular Response to Infection
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953153/
https://ncbi.nlm.nih.gov/pubmed/20810735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00900-10
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