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Inhibition of Intrahepatic Gamma Interferon Production by Hepatitis C Virus Nonstructural Protein 5A in Transgenic Mice

Hepatitis C virus (HCV) utilizes strategies to suppress or evade the host immune response for establishment of persistent infection. We have shown previously that HCV nonstructural protein 5A (NS5A) impairs tumor necrosis factor alpha (TNF-α)-mediated apoptosis. In this study, we have examined the i...

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Detalhes bibliográficos
Main Authors: Kanda, Tatsuo, Steele, Robert, Ray, Ranjit, Ray, Ratna B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738187/
https://ncbi.nlm.nih.gov/pubmed/19553305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00751-09
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