Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the EBV-encoded nuclear antigen and sequence-specific DNA binding protein required for viral origin binding and episome maintenance during latency. EBNA1 can also bind to numerous sites in the cellular genome and can provide a host cell survival...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Tempera, Italo, De Leo, Alessandra, Kossenkov, Andrew V., Cesaroni, Matteo, Song, Hui, Dawany, Noor, Showe, Louise, Lu, Fang, Wikramasinghe, Priyankara, Lieberman, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Transformation and Oncogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702570/
https://ncbi.nlm.nih.gov/pubmed/26468528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02318-15
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