Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats

Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans. Contextual fear extinction (CFE) in rodents has been well characterized an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Burgdorf, Jeffrey, Kroes, Roger A., Zhang, Xiao-lei, Gross, Amanda L., Schmidt, Mary, Weiss, Craig, Disterhoft, John F., Burch, Ronald M., Stanton, Patric K., Moskal, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702501/
https://ncbi.nlm.nih.gov/pubmed/26210936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.07.039
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados