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Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats

Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans. Contextual fear extinction (CFE) in rodents has been well characterized an...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Behav Brain Res
Κύριοι συγγραφείς: Burgdorf, Jeffrey, Kroes, Roger A., Zhang, Xiao-lei, Gross, Amanda L., Schmidt, Mary, Weiss, Craig, Disterhoft, John F., Burch, Ronald M., Stanton, Patric K., Moskal, Joseph R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702501/
https://ncbi.nlm.nih.gov/pubmed/26210936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.07.039
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