A multi-factorial analysis of response to warfarin in a UK prospective cohort

BACKGROUND: Warfarin is the most widely used oral anticoagulant worldwide, but it has a narrow therapeutic index which necessitates constant monitoring of anticoagulation response. Previous genome-wide studies have focused on identifying factors explaining variance in stable dose, but have not explo...

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Vydáno v:Genome Med
Hlavní autoři: Bourgeois, Stephane, Jorgensen, Andrea, Zhang, Eunice J., Hanson, Anita, Gillman, Matthew S., Bumpstead, Suzannah, Toh, Cheng Hock, Williamson, Paula, Daly, Ann K., Kamali, Farhad, Deloukas, Panos, Pirmohamed, Munir
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702374/
https://ncbi.nlm.nih.gov/pubmed/26739746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0255-y
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