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7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders

Brain-derived neurotrophic factor (BDNF) regulates a variety of biological processes predominantly via binding to the transmembrane receptor tyrosine kinase TrkB. It is a potential therapeutic target in numerous neurological, mental and metabolic disorders. However, the lack of efficient means to de...

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Bibliografische gegevens
Gepubliceerd in:Transl Neurodegener
Hoofdauteurs: Liu, Chaoyang, Chan, Chi Bun, Ye, Keqiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702337/
https://ncbi.nlm.nih.gov/pubmed/26740873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-015-0048-7
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