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Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster

BACKGROUND: A generally accepted approach to the analysis of RNA-Seq read count data does not yet exist. We sequenced the mRNA of 726 individuals from the Drosophila Genetic Reference Panel in order to quantify differences in gene expression among single flies. One of our experimental goals was to i...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Lin, Yanzhu, Golovnina, Kseniya, Chen, Zhen-Xia, Lee, Hang Noh, Negron, Yazmin L. Serrano, Sultana, Hina, Oliver, Brian, Harbison, Susan T.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702322/
https://ncbi.nlm.nih.gov/pubmed/26732976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2353-z
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