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Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster

BACKGROUND: A generally accepted approach to the analysis of RNA-Seq read count data does not yet exist. We sequenced the mRNA of 726 individuals from the Drosophila Genetic Reference Panel in order to quantify differences in gene expression among single flies. One of our experimental goals was to i...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Lin, Yanzhu, Golovnina, Kseniya, Chen, Zhen-Xia, Lee, Hang Noh, Negron, Yazmin L. Serrano, Sultana, Hina, Oliver, Brian, Harbison, Susan T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702322/
https://ncbi.nlm.nih.gov/pubmed/26732976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2353-z
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