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CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver
Human cytochrome P450 (CYP) 2C enzymes metabolize ∼30% of clinically prescribed drugs and various environmental chemicals. CYP2C8, an important member of this subfamily, metabolizes the anticancer drug paclitaxel, certain antidiabetic drugs, and endogenous substrates, including arachidonic acid, to...
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| Publicat a: | Mol Pharmacol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702104/ https://ncbi.nlm.nih.gov/pubmed/26467040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.100255 |
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