The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety

The conjugated estrogen/bazedoxifene tissue-selective estrogen complex (TSEC) is designed to minimize the undesirable effects of estrogen in the uterus and breast tissues and to allow the beneficial effects of estrogen in other estrogen-target tissues, such as the bone and brain. However, the molecu...

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Udgivet i:Mol Pharmacol
Main Authors: Han, Sang Jun, Begum, Khurshida, Foulds, Charles E., Hamilton, Ross A., Bailey, Suzanna, Malovannaya, Anna, Chan, Doug, Qin, Jun, O’Malley, Bert W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702103/
https://ncbi.nlm.nih.gov/pubmed/26487511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.100925
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