Binding Mode Selection Determines the Action of Ecstasy Homologs at Monoamine Transporters

Determining the structural elements that define substrates and inhibitors at the monoamine transporters is critical to elucidating the mechanisms underlying these disparate functions. In this study, we addressed this question directly by generating a series of N-substituted 3,4-methylenedioxyampheta...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Sandtner, Walter, Stockner, Thomas, Hasenhuetl, Peter S., Partilla, John S., Seddik, Amir, Zhang, Yuan-Wei, Cao, Jianjing, Holy, Marion, Steinkellner, Thomas, Rudnick, Gary, Baumann, Michael H., Ecker, Gerhard F., Newman, Amy Hauck, Sitte, Harald H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702095/
https://ncbi.nlm.nih.gov/pubmed/26519222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.101394
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