Low stromal Foxp3(+) regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer

BACKGROUND: Foxp3(+) regulatory T cells (Tregs) play a vital role in preventing autoimmunity, but also suppress antitumour immune responses. Tumour infiltration by Tregs has strong prognostic significance in colorectal cancer, and accumulating evidence suggests that chemotherapy and radiotherapy eff...

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Detaylı Bibliyografya
Yayımlandı:Br J Cancer
Asıl Yazarlar: McCoy, M J, Hemmings, C, Miller, T J, Austin, S J, Bulsara, M K, Zeps, N, Nowak, A K, Lake, R A, Platell, C F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Translational Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702002/
https://ncbi.nlm.nih.gov/pubmed/26645238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.427
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