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BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance

Melanoma can switch between proliferative and invasive states, which have identifying gene expression signatures that correlate with good and poor prognosis, respectively. However, the mechanisms controlling these signatures are poorly understood. In this study, we identify BMI1 as a key determinant...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Ferretti, Roberta, Bhutkar, Arjun, McNamara, Molly C., Lees, Jacqueline A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701976/
https://ncbi.nlm.nih.gov/pubmed/26679841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.267757.115
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