Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss

The Neuroplastin gene encodes two synapse-enriched protein isoforms, Np55 and Np65, which are transmembrane glycoproteins that regulate several cellular processes, including the genesis, maintenance, and plasticity of synapses. We found that an absence of Np65 causes early-onset sensorineural hearin...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Neurosci
المؤلفون الرئيسيون: Carrott, Leanne, Bowl, Michael R., Aguilar, Carlos, Johnson, Stuart L., Chessum, Lauren, West, Melissa, Morse, Susan, Dorning, Joanne, Smart, Elizabeth, Hardisty-Hughes, Rachel, Ball, Greg, Parker, Andrew, Barnard, Alun R., MacLaren, Robert E., Wells, Sara, Marcotti, Walter, Brown, Steve D.M.
التنسيق: Artigo
اللغة:Inglês
منشور في: Society for Neuroscience 2016
الموضوعات:
Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701962/
https://ncbi.nlm.nih.gov/pubmed/26740663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1808-15.2016
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