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Aurora-A Kinase as a Promising Therapeutic Target in Cancer

Mammalian Aurora family of serine/threonine kinases are master regulators of mitotic progression and are frequently overexpressed in human cancers. Among the three members of the Aurora kinase family (Aurora-A, -B, and -C), Aurora-A and Aurora-B are expressed at detectable levels in somatic cells un...

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Veröffentlicht in:Front Oncol
Hauptverfasser: D’Assoro, Antonino B., Haddad, Tufia, Galanis, Evanthia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701905/
https://ncbi.nlm.nih.gov/pubmed/26779440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00295
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