Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.

Cathepsin D (EC 3.4.23.5) is a lysosomal protease suspected to play important roles in protein catabolism, antigen processing, degenerative diseases, and breast cancer progression. Determination of the crystal structures of cathepsin D and a complex with pepstatin at 2.5 A resolution provides insigh...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Baldwin, E T, Bhat, T N, Gulnik, S, Hosur, M V, Sowder, R C, Cachau, R E, Collins, J, Silva, A M, Erickson, J W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC47019/
https://ncbi.nlm.nih.gov/pubmed/8393577
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky