Deletion of IGF-1 Receptors in Cardiomyocytes Attenuates Cardiac Aging in Male Mice

IGF-1 receptor (IGF-1R) signaling is implicated in cardiac hypertrophy and longevity. However, the role of IGF-1R in age-related cardiac remodeling is only partially understood. We therefore sought to determine whether the deletion of the IGF-1R in cardiomyocytes might delay the development of aging...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Ock, Sangmi, Lee, Wang Soo, Ahn, Jihyun, Kim, Hyun Min, Kang, Hyun, Kim, Ho-Shik, Jo, Daewoong, Abel, E. Dale, Lee, Tae Jin, Kim, Jaetaek
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701888/
https://ncbi.nlm.nih.gov/pubmed/26469138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1709
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