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Deletion of IGF-1 Receptors in Cardiomyocytes Attenuates Cardiac Aging in Male Mice
IGF-1 receptor (IGF-1R) signaling is implicated in cardiac hypertrophy and longevity. However, the role of IGF-1R in age-related cardiac remodeling is only partially understood. We therefore sought to determine whether the deletion of the IGF-1R in cardiomyocytes might delay the development of aging...
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| Publicat a: | Endocrinology |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Endocrine Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701888/ https://ncbi.nlm.nih.gov/pubmed/26469138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1709 |
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