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The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch
Human leukocyte antigen (HLA)-E molecules are potent inhibitors of NK cell-mediated killing. Low in polymorphisms, two alleles are widely expressed among diverse populations: HLA-E*01:01 and HLA-E*01:03. Both alleles are distinguished by one SNP resulting in the substitution Arg107Gly. Both alleles...
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| Publicado no: | Immunogenetics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701785/ https://ncbi.nlm.nih.gov/pubmed/26552660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-015-0880-z |
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