The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch

Human leukocyte antigen (HLA)-E molecules are potent inhibitors of NK cell-mediated killing. Low in polymorphisms, two alleles are widely expressed among diverse populations: HLA-E*01:01 and HLA-E*01:03. Both alleles are distinguished by one SNP resulting in the substitution Arg107Gly. Both alleles...

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Bibliographic Details
Published in:Immunogenetics
Main Authors: Celik, Alexander A., Kraemer, Thomas, Huyton, Trevor, Blasczyk, Rainer, Bade-Döding, Christina
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2015
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701785/
https://ncbi.nlm.nih.gov/pubmed/26552660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-015-0880-z
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