Progesterone receptor membrane component-1 regulates hepcidin biosynthesis

Iron homeostasis is tightly regulated by the membrane iron exporter ferroportin and its regulatory peptide hormone hepcidin. The hepcidin/ferroportin axis is considered a promising therapeutic target for the treatment of diseases of iron overload or deficiency. Here, we conducted a chemical screen i...

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Pubblicato in:J Clin Invest
Autori principali: Li, Xiang, Rhee, David K., Malhotra, Rajeev, Mayeur, Claire, Hurst, Liam A., Ager, Emily, Shelton, Georgia, Kramer, Yael, McCulloh, David, Keefe, David, Bloch, Kenneth D., Bloch, Donald B., Peterson, Randall T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701562/
https://ncbi.nlm.nih.gov/pubmed/26657863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83831
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