Endothelial LRP1 transports amyloid-β(1–42) across the blood-brain barrier

According to the neurovascular hypothesis, impairment of low-density lipoprotein receptor–related protein-1 (LRP1) in brain capillaries of the blood-brain barrier (BBB) contributes to neurotoxic amyloid-β (Aβ) brain accumulation and drives Alzheimer’s disease (AD) pathology. However, due to conflict...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Clin Invest
Main Authors: Storck, Steffen E., Meister, Sabrina, Nahrath, Julius, Meißner, Julius N., Schubert, Nils, Di Spiezio, Alessandro, Baches, Sandra, Vandenbroucke, Roosmarijn E., Bouter, Yvonne, Prikulis, Ingrid, Korth, Carsten, Weggen, Sascha, Heimann, Axel, Schwaninger, Markus, Bayer, Thomas A., Pietrzik, Claus U.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701557/
https://ncbi.nlm.nih.gov/pubmed/26619118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81108
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla