Nanoparticulate flurbiprofen reduces amyloid-β(42) generation in an in vitro blood–brain barrier model

INTRODUCTION: The amyloid-β(42) (Aβ(42)) peptide plays a crucial role in the pathogenesis of Alzheimer’s disease (AD), the most common neurodegenerative disorder affecting the elderly. Over the past years, several approaches and compounds developed for the treatment of AD have failed in clinical stu...

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Autors principals: Meister, Sabrina, Zlatev, Iavor, Stab, Julia, Docter, Dominic, Baches, Sandra, Stauber, Roland H, Deutsch, Mordechai, Schmidt, Reinhold, Ropele, Stefan, Windisch, Manfred, Langer, Klaus, Wagner, Sylvia, von Briesen, Hagen, Weggen, Sascha, Pietrzik, Claus U
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978673/
https://ncbi.nlm.nih.gov/pubmed/24280275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt225
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