Nanoparticulate flurbiprofen reduces amyloid-β(42) generation in an in vitro blood–brain barrier model

INTRODUCTION: The amyloid-β(42) (Aβ(42)) peptide plays a crucial role in the pathogenesis of Alzheimer’s disease (AD), the most common neurodegenerative disorder affecting the elderly. Over the past years, several approaches and compounds developed for the treatment of AD have failed in clinical stu...

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Detalhes bibliográficos
Main Authors: Meister, Sabrina, Zlatev, Iavor, Stab, Julia, Docter, Dominic, Baches, Sandra, Stauber, Roland H, Deutsch, Mordechai, Schmidt, Reinhold, Ropele, Stefan, Windisch, Manfred, Langer, Klaus, Wagner, Sylvia, von Briesen, Hagen, Weggen, Sascha, Pietrzik, Claus U
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978673/
https://ncbi.nlm.nih.gov/pubmed/24280275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt225
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