RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure

RNA splicing is a major contributor to total transcriptome complexity; however, the functional role and regulation of splicing in heart failure remain poorly understood. Here, we used a total transcriptome profiling and bioinformatic analysis approach and identified a muscle-specific isoform of an R...

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Udgivet i:J Clin Invest
Main Authors: Gao, Chen, Ren, Shuxun, Lee, Jae-Hyung, Qiu, Jinsong, Chapski, Douglas J., Rau, Christoph D., Zhou, Yu, Abdellatif, Maha, Nakano, Astushi, Vondriska, Thomas M., Xiao, Xinshu, Fu, Xiang-Dong, Chen, Jau-Nian, Wang, Yibin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701548/
https://ncbi.nlm.nih.gov/pubmed/26619120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84015
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