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p21(CDKN1A) Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates
The cell cycle inhibitor p21(CDKN1A) was previously found to interact directly with DNA nick-sensor poly(ADP-ribose) polymerase-1 (PARP-1) and to promote base excision repair (BER). However, the molecular mechanism responsible for this BER-related association of p21 with PARP-1 remains to be clarifi...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701469/ https://ncbi.nlm.nih.gov/pubmed/26730949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146031 |
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