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Enantioselective Pharmacokinetics of (R)- and (S)-Ketamine After a 5-Day Infusion in Patients with Complex Regional Pain Syndrome

INTRODUCTION: This study determined the pharmacokinetics and pharmacodynamics of (R)- and (S)-ketamine and (R)- and (S)-norketamine following a 5-day moderate dose, as a continuous (R,S)-ketamine infusion in complex regional pain syndrome (CRPS) patients. MATERIALS AND METHODS: Ketamine was titrated...

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Detalhes bibliográficos
Publicado no:Chirality
Main Authors: GOLDBERG, MICHAEL E., TORJMAN, MARC C., SCHWARTZMAN, ROBERT J., MAGER, DONALD E., WAINER, IRVING W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701199/
https://ncbi.nlm.nih.gov/pubmed/20803495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chir.20890
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