Combined Interactions of Plant Homeodomain and Chromodomain Regulate NuA4 Activity at DNA Double-Strand Breaks

DNA double-strand breaks (DSBs) represent one of the most threatening lesions to the integrity of genomes. In yeast Saccharomyces cerevisiae, NuA4, a histone acetylation complex, is recruited to DSBs, wherein it acetylates histones H2A and H4, presumably relaxing the chromatin and allowing access to...

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Publicado no:Genetics
Main Authors: Su, Wen-Pin, Hsu, Sen-Huei, Chia, Li-Chiao, Lin, Jui-Yang, Chang, Song-Bin, Jiang, Zong-da, Lin, Yi-Ju, Shih, Min-Yu, Chen, Yi-Cheng, Chang, Mau-Sun, Yang, Wen-Bin, Hung, Jan-Jong, Hung, Po-Cheng, Wu, Wei-Sheng, Myung, Kyungjae, Liaw, Hungjiun
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701104/
https://ncbi.nlm.nih.gov/pubmed/26564157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.184432
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