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Antisense Transcription of Retrotransposons in Drosophila: An Origin of Endogenous Small Interfering RNA Precursors

Movement of transposons causes insertions, deletions, and chromosomal rearrangements potentially leading to premature lethality in Drosophila melanogaster. To repress these elements and combat genomic instability, eukaryotes have evolved several small RNA-mediated defense mechanisms. Specifically, i...

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Foilsithe in:Genetics
Main Authors: Russo, Joseph, Harrington, Andrew W., Steiniger, Mindy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701079/
https://ncbi.nlm.nih.gov/pubmed/26534950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.177196
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