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Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain

The comparative genomics revolution of the past decade has enabled the discovery of functional elements in the human genome via sequence comparison. While that is so, an important class of elements, those specific to humans, is entirely missed by searching for sequence conservation across species. H...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Schrider, Daniel R., Kern, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700959/
https://ncbi.nlm.nih.gov/pubmed/26590212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv228
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