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Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain

The comparative genomics revolution of the past decade has enabled the discovery of functional elements in the human genome via sequence comparison. While that is so, an important class of elements, those specific to humans, is entirely missed by searching for sequence conservation across species. H...

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Pubblicato in:Genome Biol Evol
Autori principali: Schrider, Daniel R., Kern, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700959/
https://ncbi.nlm.nih.gov/pubmed/26590212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv228
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