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Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora
BACKGROUND: Isepamicin is a weakly toxic but highly active aminoglycoside antibiotic derivative of gentamicin B. Gentamicin B is a naturally occurring minor component isolated from Micromonospora echinospora. 2ʹ-NH(2)-containing gentamicin C complex is a dominant compound produced by wild-type M. ec...
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| Veröffentlicht in: | Microb Cell Fact |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700567/ https://ncbi.nlm.nih.gov/pubmed/26729212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0402-6 |
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