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Aim-less translation: loss of Saccharomyces cerevisiae mitochondrial translation initiation factor mIF3/Aim23 leads to unbalanced protein synthesis

The mitochondrial genome almost exclusively encodes a handful of transmembrane constituents of the oxidative phosphorylation (OXPHOS) system. Coordinated expression of these genes ensures the correct stoichiometry of the system’s components. Translation initiation in mitochondria is assisted by two...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kuzmenko, Anton, Derbikova, Ksenia, Salvatori, Roger, Tankov, Stoyan, Atkinson, Gemma C., Tenson, Tanel, Ott, Martin, Kamenski, Piotr, Hauryliuk, Vasili
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700529/
https://ncbi.nlm.nih.gov/pubmed/26728900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18749
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