EBP50 induces apoptosis in macrophages by upregulating nitric oxide production to eliminate intracellular Mycobacterium tuberculosis

Mycobacterium bovis BCG is known to have the capacity to inhibit the positioning of iNOS on BCG-containing phagosomes by interfering with EBP50, a scaffolding protein that controls the recruitment of inducible nitric oxide synthase (iNOS) at the vicinity of phagosomes in macrophages. However, knockd...

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Publicat a:Sci Rep
Autors principals: Guo, Yang, Deng, Yating, Huang, Zikun, Luo, Qing, Peng, Yiping, Chen, Jie, Jiang, Hong, Ye, Jianqing, Li, Junming
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700441/
https://ncbi.nlm.nih.gov/pubmed/26729618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18961
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