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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
Short RNAs mediate gene silencing, a process associated with virus resistance, developmental control and heterochromatin formation in eukaryotes(1–5). RNA silencing is initiated through Dicer-mediated processing of double-stranded RNA into small interfering RNA (siRNA)(6,7). The siRNA guide strand a...
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| Udgivet i: | Nature |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700412/ https://ncbi.nlm.nih.gov/pubmed/15152257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02519 |
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