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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

Short RNAs mediate gene silencing, a process associated with virus resistance, developmental control and heterochromatin formation in eukaryotes(1–5). RNA silencing is initiated through Dicer-mediated processing of double-stranded RNA into small interfering RNA (siRNA)(6,7). The siRNA guide strand a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Ma, Jin-Biao, Ye, Keqiong, Patel, Dinshaw J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700412/
https://ncbi.nlm.nih.gov/pubmed/15152257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02519
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