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Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab

Giant cell tumor (GCT) of bone is a generally benign, but often locally aggressive, neoplasm of bone, with a propensity for recurrence. Sarcomatous transformation is rare and typically occurs with a history of recurrences and radiation treatment. Denosumab, an inhibitor of the RANK ligand involved i...

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Publicat a:Case Rep Med
Autors principals: Broehm, Cory Julian, Garbrecht, Erika L., Wood, Jeff, Bocklage, Therese
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700156/
https://ncbi.nlm.nih.gov/pubmed/26798348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/767198
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