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Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

Alzheimer’s disease (AD) is an age-related neurodegenerative disease marked by a progressive cognitive decline. Metabolic impairments are common hallmarks of AD, and amyloid-β (Aβ) peptide and hyperphosphorylated tau protein—the two foremost histopathological signs of AD—have been implicated in mito...

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Detalles Bibliográficos
Publicado en:Cell Mol Life Sci
Main Authors: Grimm, Amandine, Biliouris, Emily E., Lang, Undine E., Götz, Jürgen, Mensah-Nyagan, Ayikoe Guy, Eckert, Anne
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700074/
https://ncbi.nlm.nih.gov/pubmed/26198711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-1988-x
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