Inhibition of the Mitochondrial Enzyme ABAD Restores the Amyloid-β-Mediated Deregulation of Estradiol

Alzheimer's disease (AD) is a conformational disease that is characterized by amyloid-β (Aβ) deposition in the brain. Aβ exerts its toxicity in part by receptor-mediated interactions that cause down-stream protein misfolding and aggregation, as well as mitochondrial dysfunction. Recent reports...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lim, Yun-An, Grimm, Amandine, Giese, Maria, Mensah-Nyagan, Ayikoe Guy, Villafranca, J. Ernest, Ittner, Lars M., Eckert, Anne, Götz, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236223/
https://ncbi.nlm.nih.gov/pubmed/22174920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028887
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados