Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD

BACKGROUND: Respiratory virus infections are commonly associated with COPD exacerbations, but little is known about the mechanisms linking virus infection to exacerbations. Pathogenic mechanisms in stable COPD include oxidative and nitrosative stress and reduced activity of histone deacetylase-2 (HD...

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Détails bibliographiques
Publié dans:Chest
Auteurs principaux: Footitt, Joseph, Mallia, Patrick, Durham, Andrew L., Ho, W. Eugene, Trujillo-Torralbo, Maria-Belen, Telcian, Aurica G., Del Rosario, Ajerico, Chang, Cheng, Peh, Hong-Yong, Kebadze, Tatiana, Aniscenko, Julia, Stanciu, Luminita, Essilfie-Quaye, Sarah, Ito, Kazuhiro, Barnes, Peter J., Elkin, Sarah L., Kon, Onn M., Wong, W. S. Fred, Adcock, Ian M., Johnston, Sebastian L.
Format: Artigo
Langue:Inglês
Publié: American College of Chest Physicians 2016
Sujets:
Original Research: COPD
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700054/
https://ncbi.nlm.nih.gov/pubmed/25790167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.14-2637
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