Doubly Spin-Labeled RNA as an EPR Reporter for Studying Multicomponent Supramolecular Assemblies

mRNAs are involved in complicated supramolecular complexes with human 40S and 80S ribosomes responsible for the protein synthesis. In this work, a derivative of nonaribonucleotide pUUCGUAAAA with nitroxide spin labels attached to the 5′-phosphate and to the C8 atom of the adenosine in sixth position...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Malygin, Alexey A., Graifer, Dmitri M., Meschaninova, Maria I., Venyaminova, Aliya G., Krumkacheva, Olesya A., Fedin, Matvey V., Karpova, Galina G., Bagryanskaya, Elena G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699879/
https://ncbi.nlm.nih.gov/pubmed/26682820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.042
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