Structural rearrangements in mRNA upon its binding to human 80S ribosomes revealed by EPR spectroscopy

The model mRNA (MR), 11-mer RNA containing two nitroxide spin labels at the 5′- and 3′-terminal nucleotides and prone to form a stable homodimer (MR)(2), was used for Electron Paramagnetic Resonance study of structural rearrangements in mRNA occurring upon its binding to human 80S ribosomes. The for...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Malygin, Alexey A, Graifer, Dmitri M, Meschaninova, Maria I, Venyaminova, Alya G, Timofeev, Ivan O, Kuzhelev, Andrey A, Krumkacheva, Olesya A, Fedin, Matvey V, Karpova, Galina G, Bagryanskaya, Elena G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
RNA Prot Comp
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778603/
https://ncbi.nlm.nih.gov/pubmed/29156000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1136
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