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Accumulation of Aspartic Acid(421)- and Glutamic Acid(391)-Cleaved Tau in Neurofibrillary Tangles Correlates With Progression in Alzheimer Disease
Truncations of tau protein at aspartic acid(421) (D(421)) and glutamic acid(391) (E(391)) residues are associated with neurofibrillary tangles (NFTs) in the brains of Alzheimer disease (AD) patients. Using immunohistochemistry with antibodies to D(421)- and E(391)-truncated tau (Tau-C3 and MN423, re...
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| Publicado en: | J Neuropathol Exp Neurol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699801/ https://ncbi.nlm.nih.gov/pubmed/18431250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31817275c7 |
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